Excited to share our latest work published in Nature Communications

👉 https://doi.org/10.1038/s41467-025-60543-5

🧠 In this study, we uncover a novel pharmacological action of memantine, a well-known FDA-approved drug for Alzheimer’s disease. Beyond its established role as an NMDA receptor antagonist, we show that memantine also inhibits calcium-permeable AMPA receptors (CP-AMPARs)—key players in neurodegenerative and neurodevelopmental disorders.

Proud to be part of this interdisciplinary collaboration with researchers at UTHealth and Johns Hopkins University!